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www.indivumed.com/approach/unique-database/

Excellent data is the key to precision oncology.

Take a look into the world’s most comprehensive highquality multiomics cancer database

Unique Database Multi-omics data of unparalleled quality

An in-depth multi-omics analysis of matched tumor and normal tissue, collected and processed in a standardized way, is the foundation of Indivumed’s R&D programs. Following this approach of global clinical collaboration over decades, we can now draw on a proprietary database that reflects the molecular reality of cancer at a level never seen before. This is the key to our cutting-edge data analytics for innovative target and drug discovery.

In-depth data that reflects the biological reality of cancer

Clinical data

  • Up to 320 data points per patient
  • Up to ten years of follow-up data

Multi-omics processing

On both tumor and normal tissue

  • Whole genomics
  • Whole transcriptomics
  • Small RNAs
  • Total proteomics
  • Phosphoproteomics
  • More depending on the project

Digital pathology

  • H&E stain scans
  • FFPE sections for IHC

Diverse cancer types

  • CRC, NLCLC, Breast Cancer, and others
  • Samples collected globally (Asia, Europe, Americas)

Cancer is an incredibly complex disease – no single layer of data is enough to fully understand it.

There was no data that matched our ambitions. So, we created our own.

We extract multi-omics information from matched tumor and normal tissue samples using next-generation sequencing and mass spectrometry technologies. However, it is not the technology that makes our data unique, but the exceptional quality of our samples. The key innovation on which our excellent data quality is based today is our rapid SOP-guided tissue collection and conservation process.

Ten minutes make all the difference.

It takes years for novel drugs to reach the market, however, the first ten minutes in the collection, processing, and conservation process are crucial. Research shows that minimizing ischemia time has a major impact on the integrity of tissue samples and is very important to preserve the expression of otherwise undetectable therapeutic targets.

Comprehensive data

“An incomplete picture of cancer biology leads researchers to overlook potentially important targets or waste time and money on false leads.”

Dr. Silvia von der Heyde | Senior Data Scientist

Tissue collection SOPs Special surgery procedures to protect sample integrity

While surgeons focus on removing the tumor and pathologists on subsequent tissue diagnostics, there is routinely no attention to the proper conservation of patient material that could be used for further biomedical research. That is why we, together with surgeons and oncologists from around global clinical network, have developed over the years a series of special standard operating procedures (SOPs) for the collection and preservation of tissue samples. These procedures, including keeping cold ischemia times to under ten minutes, ensure pre-analytically controlled specimens with a very high sample integrity.

Our clinical network provides us with access to high-quality samples and data.